Pfizer 8-K

EarningsGuidance reaffirmedImpairment / charge

Lower Comirnaty and Paxlovid sales outweighed growth elsewhere; FY2026 guidance reaffirmed despite pricing, tariff and exclusivity headwinds.

Filed 2026-02-03 07:01 ET

Summary

FY2025 and Q4 results with FY2026 guidance reaffirmed. Revenue declined as lower Comirnaty and Paxlovid sales outweighed growth elsewhere; operational revenue excluding those products rose 6% for FY and 9% for Q4. The outlook includes ≈$5B in 2026 COVID-19 product revenue and an expected ≈$1.5B Y/Y revenue impact from loss of exclusivity, alongside unfavorable Most-Favored-Nation pricing, TrumpRx and tariffs.

Key Figures

Metric Q4 2025 Q4 2024 Y/Y
Revenue $17.6B $17.8B (1%)
Reported net income/(loss) attributable to Pfizer Inc. common shareholders $(1.65)B $410M n/m
Adjusted income, non-GAAP $3.79B $3.59B 5%
Reported diluted EPS/(LPS) $(0.29) $0.07 n/m
Adjusted diluted EPS, non-GAAP $0.66 $0.63 5%
Metric FY2025 FY2024 Y/Y
Revenue $62.6B $63.6B (2%)
Reported net income attributable to Pfizer Inc. common shareholders $7.77B $8.03B (3%)
Adjusted income, non-GAAP $18.4B $17.7B 4%
Reported diluted EPS $1.36 $1.41 (3%)
Adjusted diluted EPS, non-GAAP $3.22 $3.11 4%
  • Revenue declines reflected lower COVID-19 product sales: Comirnaty fell 35% operationally in Q4 and 20% for FY; Paxlovid fell 70% and 59%, respectively. Growth in products including Abrysvo, Eliquis, the Vyndaqel family and oncology products partly offset the declines.
  • Q4 reported results included $4.36B of non-cash intangible asset impairments; full-year impairments were $4.94B, primarily reflecting changed development plans and updated commercial forecasts.
  • FY2025 shareholder returns included $9.8B in cash dividends ($1.72 per share); Pfizer made no share repurchases. Its remaining authorization was $3.3B as of 2/3/2026.

Guidance

Metric Period Guidance Prior Direction
Revenue FY2026 $59.5B-$62.5B — Reaffirmed
Selling, informational and administrative expenses, adjusted FY2026 $12.5B-$13.5B — Reaffirmed
R&D expenses, adjusted FY2026 $10.5B-$11.5B — Reaffirmed
Effective tax rate on adjusted income FY2026 Approximately 15.0% — Reaffirmed
Diluted EPS, adjusted non-GAAP FY2026 $2.80-$3.00 — Reaffirmed

Investor Takeaways

  • Watch progress toward ≈20 planned key pivotal study starts in 2026, including ten trials for ultra-long-acting obesity assets acquired from Metsera.
  • Pfizer expects to complete its sale of its 11.7% ViiV Healthcare stake for $1.875B cash in Q1 2026, subject to regulatory clearances.

The summary is written by an AI model reading the filing.

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