Schrödinger, Inc. 8-K

EarningsGuidance reaffirmed

Hosted licensing shift cut software revenue despite ACV growth; Lilly’s Ajax acquisition includes milestone-linked payments.

Filed 2026-05-05 16:06 ET

Summary

Q1 2026 results with Q2 and FY2026 outlook. ACV grew 12%, while total revenue declined 2% as the planned shift to hosted software licensing reduced software revenue; drug discovery revenue rose on accelerated recognition of deferred collaboration revenue. Lilly’s announced acquisition of Ajax for up to $2.3B, where Schrödinger held a 5.8% stake at year-end 2025, includes additional payments tied to clinical and regulatory milestones.

Key Figures

Metric Q1 2026 Q1 2025 Y/Y
Revenue $58.6M $59.6M -1.6%
Loss from operations $(48.8)M $(50.9)M n/m
Net loss (GAAP) $(60.0)M $(59.8)M n/m
Adjusted EBITDA (non-GAAP) $(37.7)M $(37.3)M n/m
Diluted EPS $(0.81) $(0.82) n/m
Operating cash flow $(14.8)M $144M n/m
ACV (operating metric) $28.4M — 12%
  • Software revenue fell 21% to $35.6M, reflecting the planned accelerated transition to hosted licensing. Drug discovery revenue rose to $22.9M from $10.2M, driven by deferred revenue recognition as collaborations progressed and the discontinuation of one program; contribution revenue was $0.148M vs $4.34M, primarily due to completion of a grant.
  • Cash, cash equivalents, restricted cash and marketable securities totaled $406M at quarter-end. Operating expenses were $78.3M, down 4% Y/Y.

Guidance

Metric Period Guidance Prior Direction
ACV (operating metric) FY2026 $218M-$228M; 10%-15% growth over 2025 — Reaffirmed
Drug discovery revenue (GAAP) FY2026 $55M-$65M — Reaffirmed
Operating expenses FY2026 Less than 2025 — Reaffirmed
ACV (operating metric; excluding contribution ACV) Q2 2026 $19M-$23M — —

Investor Takeaways

  • Track Q2 and FY2026 ACV against the stated ranges, alongside FY drug discovery revenue and operating expense outlook.
  • Schrödinger plans an early-access release of Bunsen, its agentic AI co-scientist, this summer; adoption and utilization will test the expected expansion of platform use.
  • Ajax-related payments beyond the upfront amount depend on clinical and regulatory milestones.

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