Myriad Genetics 8-K

EarningsGuidance reaffirmedImpairment / charge

UnitedHealthcare’s coverage change hit GeneSight sales and offset Q4 growth; Prenatal volume fell amid an order-system transition.

Filed 2026-02-23 16:07 ET

Summary

Q4 and FY2025 results with FY2026 guidance reiterated. Q4 revenue was flat Y/Y as reported, but grew 4% excluding an $8.1M UnitedHealthcare coverage headwind. FY2025 revenue fell 2%, or grew 2% excluding the UnitedHealthcare headwind and the EndoPredict divestiture.

Key Figures

Metric Q4 2025 Q4 2024 Y/Y
Revenue $209.8M $210.6M 0%
Operating loss $(5.7)M $(39.0)M n/m
Net loss $(7.9)M $(42.5)M n/m
Adjusted EBITDA (non-GAAP) $14.3M $10.6M 34.9%
Diluted EPS $(0.08) $(0.47) n/m
Adjusted diluted EPS (non-GAAP) $0.04 $0.03 33.3%
Operating cash flow $10.6M $6.6M 60.6%
Adjusted operating cash flow (non-GAAP) $17.9M $15.4M 16.2%
Adjusted free cash flow (non-GAAP) $11.9M $9.5M 25.3%
Test volume 382,000 374,000 2%
  • FY2025 revenue was $824.5M vs $837.6M, down 2%; net loss was $(365.9)M vs $(127.3)M, including $319.4M of goodwill and long-lived asset impairment, primarily associated with Mental Health and Women’s Health. Adjusted EBITDA was $38.9M vs $40.4M; adjusted diluted EPS was $0.06 vs $0.14.
  • Q4 test-volume growth included Hereditary cancer +9%, Mental Health +9% and Tumor Profiling flat; Prenatal volume fell 6% amid transition to a new order management system. GeneSight revenue was down 10%, reflecting the UnitedHealthcare coverage change.
  • Cash and cash equivalents were $149.6M at year-end vs $102.4M a year earlier; balance-sheet long-term debt was $119.9M vs $39.6M.

Guidance

Metric Period Guidance Prior Direction
Revenue FY2026 $860M-$880M — Reaffirmed
Adjusted gross margin (non-GAAP) FY2026 68%-69% — —
Adjusted EBITDA (non-GAAP) FY2026 $37M-$49M — —
Revenue Q1 2026 $200M-$203M; 2%-4% growth Y/Y — —
Adjusted EBITDA (non-GAAP) Q1 2026 Near breakeven — —
Revenue 2H 2026 Greater than 1H 2026 — —

The company does not provide forward GAAP gross margin or net income guidance because it cannot reconcile those measures without unreasonable effort.

Investor Takeaways

  • Watch the planned Precise MRD targeted alpha launch for breast cancer in March 2026, AI-enabled Prolaris commercial launch in Q2 2026, and FirstGene launch in 2H 2026.
  • Prenatal volume recovery and the company’s expectation of reaccelerating prenatal growth in coming quarters remain key operating developments.

The summary is written by an AI model reading the filing.

Model 005 · prompt 01d34d48e3

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